Part 5 of 5
AI in Genomics Series
The Future: Generative AI in Genomics
November 23, 2025
20 min read
RW
Ryan Wentzel
Founder & CEO, Humanome.AI
We are entering the era of Generative AI. Just as LLMs can write text, they can now "write" biology.
Genomic Foundation Models
Models like HyenaDNA and Nucleotide Transformer are trained on raw DNA sequences. They can predict regulatory elements, chromatin accessibility, and even gene expression levels directly from sequence.
Synthetic Biology
Generative models are being used to design novel proteins and enzymes that do not exist in nature, opening new frontiers in drug discovery and gene therapy.