The Humanome.AI Difference
We combine modern AI variant interpretation with whole-genome sequencing to build the most comprehensive genomic-insights platform we can. Today you can preview the full pipeline on a public reference genome while we complete the controls for public launch.
A Complete Picture of the Genome
Unlike typical DNA tests that read less than 1% of the genome, Humanome is built around whole genome sequencing (WGS) and whole exome sequencing (WES) — 100% of the coding genome. During this alpha we demonstrate the full pipeline end-to-end on the public GIAB NA12878 reference genome (not a customer sample, not clinical output).
AI-Powered Variant Interpretation
Our variant-classification engine applies ACMG/AMP guidelines and correlates findings against ClinVar and gnomAD. You can see exactly how it works today on the NA12878 reference genome; when public ordering opens, the same pipeline will run on your own sequencing results.
Designed for Continuous Re-Analysis
Genomic science evolves, so the interpretation should too. The Sentinel monitoring system is designed to re-scan a genome as new ClinVar/gnomAD releases land and surface reclassifications. We run this against the reference genome today; per-customer monitoring follows public launch.
Privacy-First Architecture
Humanome is built on HIPAA-aligned data protocols: we never sell personal information, data is encrypted at rest, and the design keeps you in control of your own data. Full clinical-grade controls and a signed BAA are prerequisites we are completing before public ordering opens.
Lab-Grade Sequencing, Planned
The planned consumer flow is a single sample collection at a partner lab (Quest Diagnostics integration is in development), feeding the same sequencing-and-interpretation pipeline you can preview today on the reference genome. Public collection opens after FDA notification.
Powered by Advanced AI
Our interpretation engine goes beyond simple database lookups, combining ACMG/AMP criteria with the ClinVar and gnomAD reference databases to classify variants. You can watch it run today on the public NA12878 reference genome — not clinical output, and not a diagnosis.
- ACMG/AMP guideline-compliant variant classification
- Real-time ClinVar and gnomAD database integration
- Pharmacogenomic drug-gene interaction analysis
- Continuous re-analysis with new research discoveries
- Natural language variant interpretation summaries
- Clinical trial matching for relevant findings
Humanome.AI Engine
Real-time variant analysis
Best-in-Breed Technology Partners
We are building on industry-standard tools and databases so every step of the sequencing-and-interpretation pipeline meets a high quality bar. Lab integrations are in development ahead of public launch.
Quest Diagnostics
Laboratory Partner
Industry-leading clinical laboratory with 2,200+ patient service centers nationwide for convenient sample collection.
Google DeepVariant
Variant Calling
State-of-the-art deep learning technology for highly accurate variant identification from sequencing data.
ClinVar & gnomAD
Reference Databases
Authoritative genomic databases providing clinical significance and population frequency data for variant interpretation.
Google Cloud Platform
Infrastructure
Enterprise-grade cloud infrastructure with HIPAA-aligned controls, ensuring secure and scalable genomic data processing.
Privacy by Design
Genetic information is among the most sensitive data a person owns, so the platform is built around encryption at rest and in transit, HIPAA-aligned controls, and strict access controls. A signed BAA and full clinical-grade controls are prerequisites we are completing before any real customer data is handled.
HIPAA-Aligned
Controls designed against healthcare privacy regulations
Data Encryption
AES-256 encryption at rest and in transit
You Own Your Data
Download or delete your data at any time